Professor Donald McDonald at San Francisco is one of the pioneers in vascular field and received several distinguished honors including Judah Folkman Memorial Lectureship. His laboratory has revealed cellular mechanisms of vascular and lymphatic changes involved in cancer and chronic inflammation and contributed to the understanding on the disease pathophysiology. Recent findings by his group include effects of oncolytic vaccinia virus infection of endothelial cells on tumor angiogenesis, tumor cell killing, invasion, and metastasis. He will talk about endothelial heterogeneity in normal and pathological contexts.
