Stem cells have drawn attention as an attractive cell source for tissue regeneration. Angiogenesis and neovascularization also play crucial roles in tissue repair. In this session, six speakers will present recent advances in the application of stem cells for cardiovascular tissue regeneration. Prof. Takakura has identified endothelial stem cells in the pre-existing blood vessels and showed critical roles of this cell population for the maintenance of vascularity. In this session, he is going to present development and aging of endothelial stem cells. Prof. Wu has been dedicated to making fundamental discoveries in cardiovascular medicine. He is going to present how human stem cells & genomics can be used for disease modeling. Prof. Fukuda is a pioneer in research of cardiac tissue regeneration and investigation of molecular mechanism of cardiovascular diseases. He is going to present therapy of cardiac diseases by transplantation of iPSC-derived cardiomyocytes. The last speaker, Prof. Yoon, has been studied to develop regenerative therapy for ischemic cardiovascular diseases using stem cells and tissue engineering. He will present therapeutic applications of human iPSC-derived vascular cells.
(Short Talk) An Endogenous Transmembrane Protein Controls Distinct mTORC2 Functions in Normal and Leukemic Hematopoiesis in the Bone Marrow