Understanding of cellular phenotypic changes provides essential information about cellular mechanisms of tissue homeostasis and the pathogenesis of many cardiovascular diseases. In this session, we have six speakers including four regular talks and two short talks, and will discuss about cellular phenotypic changes affecting cardiovascular diseases. Dr. Jun-ichi Abe from University of Texas MD Anderson Cancer Center will talk about stress-induced premature aging in atherosclerosis. Our second speaker, Dr. Bin Zhou from Chinese Academy of Sciences will discuss about genetic fate mapping of cardiomyocyte and endothelial cell proliferation in adult mouse. Our third speaker, Dr. Toyoaki Murohara from Nagoya University will give us a talk about the therapeutic angiogenesis by autologous adipose-derived mesenchymal stem cells. Our fourth speaker, Dr. Jeong Hun Kim from Seoul National University will present about the in vivo genome editing for angiogenesis-related retinopathy. Finally, Dr. Jan Kitajewski from University of Illinois at Chicago will give us a talk about therapeutic targeting of tumor angiogenesis using endothelial cell fate mechanisms. In addition, we will have a short talk selected from the abstracts. The speaker of short talk, Dr. Riikka Kivelä from University of Helsinki will present about the reprogramming of the phenotypes of endothelial cells and EndMT by cardiovascular disease risk factors.
(Short Talk) Cardiovascular Disease Risk Factors Reprogram Cardiac Endothelial Cell Transcriptome and Promote EndMT Features