The vascular system forms as a branching network of endothelial cells that acquire identity as arterial, venous, hemogenic, or lymphatic. The developmental processes of vascular system are highly complicated and strictly controlled. In this session, we have five speakers including three regular talks and two short talks, and will discuss about the molecular mechanisms of vascular development and maintenance. Dr. Ondine Cleaver from UT Southwestern Medical Center, will talk about customized vasculatures – lessons from organoids and embryos. Our second speaker, Dr. Kathleen Caron from University of North Carolina at Chapel Hill will introduce novel modifier genes related to naturally-occurring heterogeneity of lymphatics Within a diverse genetic population. The last speaker, Dr. Wiebke Herzog from University of Münster, will give us a talk about endothelial hypoxia-inducible transcription factors regulating brain capillary development. In addition, we will have two short talks selected from the abstracts. The first speaker of short talk, Dr. Mathias Francois from University of Sydney will talk about the function of Sox7 in lymphatic morphogenesis. And Dr. Osamu Nakagawa from National Cerebral and Cardiovascular Center Research Institute, the last speaker of short talk, will present about ALK1 signal target genes in embryonic vascular endothelial cells.
Identifying Novel Modifier Genes Related to Naturally-Occurring Heterogeneity of Lymphatics Within a Diverse Genetic Population